Identifying Clinical Trials in CMS FFS Claims Data

Can we use the Claims Processing Manual to define service utilization?

The Claims Processing Manual (CPM) is the rulebook for submitting claims to CMS. It covers a wide range of medical coding instructions by clinical setting and form. As the main source of instruction on claims processing and assuming that providers are incentivized to follow submission requirements for reimbursement, it should be a reliable source for defining research methodology.